'Cannabis alters human DNA' -- new study (Eurek Alert)

[Drew Wilson]

A new study published by University of Leicester researchers has found "convincing evidence" that cannabis smoke damages DNA in ways that could potentially increase the risk of cancer development in humans.

Using a newly developed highly sensitive liquid chromatography-tandem mass spectrometry method, the University of Leicester scientists found clear indication that cannabis smoke damages DNA, under laboratory conditions.

They have now published the findings in the journal Chemical Research in Toxicology1.

The research was carried out by Rajinder Singh, Jatinderpal Sandhu, Balvinder Kaur, Tina Juren, William P. Steward, Dan Segerback and Peter B. Farmer from the Cancer Biomarkers and Prevention Group, Department of Cancer Studies and Molecular Medicine and Karolinska Institute, Sweden.

More... (http://www.eurekalert.org/pub_releases/2009-06/uol-ah061609.php)

It's times like this I'm glad I'm clean. :yikes:

[1cooldude]

wonder if that applies to a spliff?

[rainbowdemon]

Horseshit!!

[1cooldude]

do you have more conclusive proof rd?

[rainbowdemon]

Well, I was a very heavy smoker in the 70's. My daughter turned out fine. And she was a big stoner in the 90's, and she has three kids that came out fine too. That's proof enough for me!!



I'm getting pretty sick of media scare mongering. Seems to be popular now.

[Aaron_Walkhouse]

Once again, the title is spicier than the content. It's smoking http://www3.telus.net/Aaron_Walkhouse/halluc.gif
that does the damage, and if you don't burn it, it does no damage.

Here's a few numbers to remember: 226°C/435°F x 1 jiffy = 0 carcinogens

Don't forget, your ability to learn temporarily stops completely
for a couple of hours, your short term memory will be a bit weak
for about 5 and you would temporarily leave your driving skills at
the curb so save it for party time after the day's work is done and
you brought the groceries home or you may get lost and starve.
That would suck just when you get the munchies, wouldn't it? http://www3.telus.net/Aaron_Walkhouse/drool.gif

Um… better write those numbers down before you… :hypnotized: …Oh, right… never mind…

[mountain_rage]

Well, I was a very heavy smoker in the 70's. My daughter turned out fine. And she was a big stoner in the 90's, and she has three kids that came out fine too. That's proof enough for me!!



I'm getting pretty sick of media scare mongering. Seems to be popular now.

So simply because you, your daughter and none of her kids have cancer you refute the study? They visually saw the mutation, how do you refute that? Apparently cannabis doesn't enhance the logic center of ones brain.

[thepuzzler]

Don't forget, your ability to learn temporarily stops completely
for a couple of hours, Not true!

I learned Photoshop and Maya stoned off my ass. I used to sit down for hours at a time with those tutorial DVD's and a big bag of weed.

I no longer smoke weed (due to pesky drug tests at work), but everything I learnt, I learnt was done while stoned off my ass.

(And no, I haven't forgotten any of it).

[Excrement_Cranium]

Walkhouse pretty much covered it.

Smoking anything. Any smoke. Kinda like the Dr. in Super High Me saying he wouldn't recommend smoking anything, but he doesn't see marijuana as harmful.

Also covered: we are talking about possible cancer causing mutations, and these mutations would be localized by contact with the smoke. Hello lung cancer, lip cancer, mouth cancer, and throat cancer.


Smoking bad.

[drtoker]

So simply because you, your daughter and none of her kids have cancer you refute the study? They visually saw the mutation, how do you refute that?

Human error?

[moneoa]

I only smoke the best BC Greenhouse Lettuce

[mfgbypooter]

I only smoke ham, chicken, and fish.

*

[drtoker]

I only smoke the best BC Greenhouse Lettuce

So thats local for you right?
Local smoke is the best, depending on who you know ;)
The BC we get round here smells like hay, because its transported semi wet.

[thepuzzler]

Urgh, I hate that!

Mind you for a while the only weed we could get was coated in Brix+ (http://accenthydroponics.com/ecom1/prod876.htm) (Sugar solution designed to bump up profits for the commercial growers) Completely unsmokable.

Although before Brix+ came along we were getting weed that was contaminated with GLASS! (http://www.icmag.com/ic/showthread.php?t=42251&page=1&pp=15) FFS.

There was a series of major bust before all this happened, which pretty made the whole of the UK dry. It was impossible to get any uncontaminated weed for a good while after.

[RACKnRAIL]

So thats local for you right?
Local smoke is the best, depending on who you know ;)
The BC we get round here smells like hay, because its transported semi wet.

If it smells like hay, I seriously doubt its BC hydro. There are lots of outdoor operations in BC that grow various strains of pot. It goes to all parts of the country and even out of the country. People just pass it off as the best BC bud, because it sells better. You have no guarantees. nada!

I've seen some excellent outdoor strains, as I've grown for many years myself. Even hydroponically grown weed has many many different strains. There are strains that have been grown in BC for decades, but how does one know if it's a BC strain or Hawaiian or South American? Do you?

Even indoor hydroponics has several methods of producing all different kinds and levels of potencies. So many variables!! There's also the dealer's end of it... "Oh yeah, this is awesome BC bud dude". My friend grows it himself!!" "Sure, I believe you!!" How do you know? Just because some dude says it is, does that make it Columbian or British Columbian?

Trust me, good BC bud is not something you would know unless you personally grow or know the grower personally. Each grower has their own secrets and methods for growing. What clones do I use? Where do you get the clones? And most importantly, what strain are the clones? How long have I been cloning a particular strain?

The bottom line is that even in BC you can find good weed grown by pros and shit weed grown by amateurs. Some use natural fertilizers some don't. Some flush the weed of fertilizers properly, some don't. Improper methods can produce shit tasting weed too. So many variables!!

So if your BC bud smells like hay, it's because it could have been one of many outdoor or indoor strains from anywhere. Was it grown by amateurs or pros? That is the big question. With such a demand and huge profit to be made, new cultivators are popping up everywhere. Many are operated now by gangs.

[moneoa]

So if your BC bud smells like hayIt's most likely grown by angels or scorpions and smells like wet hay and is wet because when it's time to crop it's hacked down in a hurry for market.

Drug abuse if you ask me

[RACKnRAIL]

It's most likely grown by angels or scorpions and smells like wet hay and is wet because when it's time to crop it's hacked down in a hurry for market.

Drug abuse if you ask me


I know a few HA's here on the island. I will ask them about the hay smell in their weed. LOL...as if!

There is nothing worse than wet bud at harvest time. It can mold very quickly ruining the entire crop. I manicured mass quantities of outdoor bud for some people I know here on the island. It took about 10 of us 2 weeks to trim the bud, with all of us working 10 hours a day. It was a shitload of weed. We lost some to wet weather, but what a crop. The quality was average. No hay smell.

[whitenoise22]

What.............?

[mfgbypooter]

It smells like that because it is hay.

you got ripped off.

*

[RACKnRAIL]

It smells like that because it is hay.

you got ripped off.

*



I hope you're not going to start using colored fonts and posting new open trackers.

[mfgbypooter]

lol, thats just super.

*

[RACKnRAIL]

It was just the change of font thing that got me*

[fleecy]

think i got enough second-hand at the concerts this weekend.... wonder if i've mutated?

meh, likely too late for me anyway :)

[1cooldude]

nothing wrong with a bit of good 'erb.


...The quality was average

..everything starts with a high quality seed.

[drtoker]

nothing wrong with a bit of good 'erb.

[QOUTE]...The quality was average

..everything starts with a high quality seed.[/QUOTE]

Thats a load to some extent. Genetics play an important role, but good genetics can exist in poorly grown herb as well. Diamond in the rough.

[mfgbypooter]

the only quality a seed really needs to have is be viable.

*

[carpefile]

So simply because you, your daughter and none of her kids have cancer you refute the study? They visually saw the mutation, how do you refute that? Apparently cannabis doesn't enhance the logic center of ones brain.
They visually saw the mutation? Really? Did you see the study?
They saw increased levels of potentially cancer causing chemicals in a calf's thymus after exposing it to the equivalent of 10 joints. In comparison, they found no significant difference in the level of these same adducts in human lung dna between non-smokers and those who smoked 10 joints.

Seems like they made quite a leap to their conclusion based upon the data set they had.

http://www.ncbi.nlm.nih.gov/pubmed/19449825

[geraldhansen]

this is totally not true....

[sudilav]

So simply because you, your daughter and none of her kids have cancer you refute the study? They visually saw the mutation, how do you refute that? Apparently cannabis doesn't enhance the logic center of ones brain.


Now while i don't know much about chemistry, i have learn't about mass spectrometry and it damages the object it is "spectoring :P".
Anyway i'm screwed already, diet coke, cigarettes, beer, and some of that good stuff mentioned alot in this thread... What can i say, i have a very addictive personality? and yes, you can get addicted to diet coke..

As for this whole DNA damage thing, i won't try and deny it. I'll just say this. If a cancer, were to never grow past a point of no return (death) and were to never go malignant, cancer, would not be a problem. we could keep it inside us and live long and happy lives. Well, there has been alot of, well, okay, two new improvements in medicine on this...

1). RNAi has now be reserved, so that, rather than increasing yeast mitosis it decreases mitosis to almost null. So it kills the cancer, or makes it shrink, or stops it from becoming a threat. I read that their already onto experimental trials, and if i got cancer, i'd use that seeing as i'm gonna die anyway.

2). Apparently, there's a virus, which everyone gets, except, it's so weak that you appear to get no symptons in no case. Anyone, in a research group then tested it against cancer patients and found that after 6 months, the cancer had either, not grown, or shrunk (3/10 cases were shrunk, 7/10 were not grown). This is yet unexplained but i think it's a good step towards making tobacco and alcohol legal from the age of 5 :). Don't fight drugs, fight cancer.

[fleecy]

we've all got the potential to develop cancer, but not all have our "triggers" activated.